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Abstract #0589

Improved myocardial T1 mapping technique to eliminate device-induced image artefacts for patients with implanted cardiac devices

Jiaxin Shao1, Shams Rashid1, Kim-Lien Nguyen2,3, and Peng Hu1,4

1UCLADepartment of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA, United States, 2Department of Medicine, Division of Cardiology, David Geffen School of Medicine, University of California, Los Angeles, CA, United States, 3Division of Cardiology, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA, United States, 4Biomedical Physics Inter-Departmental Graduate Program, University of California, Los Angeles, CA, United States

Current cardiac T1 mapping techniques, including the modified Look-Locker inversion-recovery (MOLLI), cannot be used effectively in patients with implanted cardiac devices due to large off-resonance induced by the device. To eliminate the device-induced image artefacts, we developed a technique by modifying the MOLLI sequence to use spoiled gradient echo readout and a wideband inversion pulse, with a new acquisition scheme and T1 estimation algorithm. The feasibility of our new technique was tested in phantom studies and validated in eight healthy volunteers and ten patients with implanted cardiac devices at 1.5 Tesla.

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