Yoshiaki Morita1, Naoaki Yamada1, Emi Tateishi2, Teruo Noguchi2, Masahiro Higashi1, and Hiroaki Naito1
1Department of Radiology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan, 2Division of Cardiology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan
Diffuse interstitial fibrosis is frequently observed in dilated cardiomyopathy (DCM). A non-invasive
method that could reliably quantify fibrosis would be preferable. In this study, we demonstrated that the T1-map-derived
ECV reflects the myocardial collagen volume fraction in DCM. Therefore, the ECV could be a useful
and practical biomarker for the detection of diffuse interstitial fibrosis that
is difficult to evaluate using only conventional LGE images.