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Abstract #0595

Myocardial extracellular volume fraction (ECV) quantified by T1 mapping can detect diffuse myocardial fibrosis in dilated cardiomyopathy (DCM): Comparison with histological collagen volume fraction by endomyocardial biopsy (EMB)

Yoshiaki Morita1, Naoaki Yamada1, Emi Tateishi2, Teruo Noguchi2, Masahiro Higashi1, and Hiroaki Naito1

1Department of Radiology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan, 2Division of Cardiology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan

Diffuse interstitial fibrosis is frequently observed in dilated cardiomyopathy (DCM). A non-invasive method that could reliably quantify fibrosis would be preferable. In this study, we demonstrated that the T1-map-derived ECV reflects the myocardial collagen volume fraction in DCM. Therefore, the ECV could be a useful and practical biomarker for the detection of diffuse interstitial fibrosis that is difficult to evaluate using only conventional LGE images.

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