Abstract #0595

Myocardial extracellular volume fraction (ECV) quantified by T1 mapping can detect diffuse myocardial fibrosis in dilated cardiomyopathy (DCM): Comparison with histological collagen volume fraction by endomyocardial biopsy (EMB)

Yoshiaki Morita¹, Naoaki Yamada¹, Emi Tateishi², Teruo Noguchi², Masahiro Higashi¹, and Hiroaki Naito¹

¹Department of Radiology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan, ²Division of Cardiology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan

Diffuse interstitial fibrosis is frequently observed in dilated cardiomyopathy (DCM). A non-invasive method that could reliably quantify fibrosis would be preferable. In this study, we demonstrated that the T1-map-derived ECV reflects the myocardial collagen volume fraction in DCM. Therefore, the ECV could be a useful and practical biomarker for the detection of diffuse interstitial fibrosis that is difficult to evaluate using only conventional LGE images.

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