Abstract #0604

Flow dynamics in a 3D printed brain aneurysm model assessed by magnetic particle imaging, magnetic resonance imaging and dynamic subtraction angiography

Jan Sedlacik¹, Andreas M. Frölich¹, Johanna Spallek², Nils D. Forkert³, Tobias D. Faizy¹, Franziska Werner^4,5, Tobias Knopp^4,5, Dieter Krause², Jens Fiehler¹, and Jan-Hendrik Buhk¹

¹Neuroradiology, UKE, Hamburg, Germany, ²Product Development and Mechanical Engineering Design, TUHH, Hamburg, Germany, ³University of Calgary, Calgary, AB, Canada, ⁴Biomedical Imaging, UKE, Hamburg, Germany, ⁵Biomedical Imaging, TUHH, Hamburg, Germany

Magnetic particle imaging (MPI) was compared with dynamic magnetic resonance imaging (MRI) and dynamic subtraction angiography (DSA) in a realistic 3D printed aneurysm model. All three methods clearly depicted a distinct pulsatile flow pattern and a delayed contrast agent outflow from the aneurysm. Despite the disadvantages of a much lower temporal resolution of the dynamic MRI and the 2D projection of the DSA, all three methods are valid tools for characterizing the hemodynamics of aneurysms. Especially the radiation free, 3D, high temporal resolution MPI method seems to be a very promising tool for imaging and characterization of hemodynamics.

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