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Abstract #0604

Flow dynamics in a 3D printed brain aneurysm model assessed by magnetic particle imaging, magnetic resonance imaging and dynamic subtraction angiography

Jan Sedlacik1, Andreas M. Frölich1, Johanna Spallek2, Nils D. Forkert3, Tobias D. Faizy1, Franziska Werner4,5, Tobias Knopp4,5, Dieter Krause2, Jens Fiehler1, and Jan-Hendrik Buhk1

1Neuroradiology, UKE, Hamburg, Germany, 2Product Development and Mechanical Engineering Design, TUHH, Hamburg, Germany, 3University of Calgary, Calgary, AB, Canada, 4Biomedical Imaging, UKE, Hamburg, Germany, 5Biomedical Imaging, TUHH, Hamburg, Germany

Magnetic particle imaging (MPI) was compared with dynamic magnetic resonance imaging (MRI) and dynamic subtraction angiography (DSA) in a realistic 3D printed aneurysm model. All three methods clearly depicted a distinct pulsatile flow pattern and a delayed contrast agent outflow from the aneurysm. Despite the disadvantages of a much lower temporal resolution of the dynamic MRI and the 2D projection of the DSA, all three methods are valid tools for characterizing the hemodynamics of aneurysms. Especially the radiation free, 3D, high temporal resolution MPI method seems to be a very promising tool for imaging and characterization of hemodynamics.

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