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Abstract #0606

Chronological evaluation of Cerebral Hemodynamics by Dynamic Susceptibility Contrast Magnetic Resonance Imaging after Indirect Bypass Surgery for Moyamoya Disease

Yosuke Ishii1,2, Tadashi Nariai1, Yoji Tanaka1, HIroshi Aihara2, Yoshio Suyama2, Shinichi Wakabayashi2, and Taketoshi Maehara1

1Neurosurgery, Tokyo Medial and Dental University, Tokyo, Japan, 2Neurosurgery, Suiseikai Kajikawa Hospital, Hiroshima, Japan

We used dynamic susceptibility contrast (DSC)-MRI to evaluate the chronological changes in hemodynamics after indirect bypass surgery for moyamoya disease. Twenty five patients who underwent indirect bypass surgery and repeated DSC–MRI measurement within the first 6 postoperative months were included. We analyzed mean transit time (MTT) delay using the cerebellum as control. Mean MTT delay in the anterior circulation area gradually decreased soon after surgery and stabilized after 3 postoperative months. Postoperative MTT delay values were significantly decreased compared with preoperative values from 1 to 2 weeks onwards. These results suggested DSC–MRI detected angiogenesis during the early postoperative stages.

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