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Abstract #0637

Deconvolving the laminar gradient echo activation profiles with the spatial PSF: an approach to revealing underlying activation patterns

Irati Markuerkiaga1 and David G. Norris1

1Donders Institute, Nijmegen, Netherlands

The specificity of GE-BOLD profiles is suspected to be degraded by intracortical veins. In this work experimentally obtained GE-BOLD profiles for different subjects are deconvolved with a laminar point spread functions obtained from a model of cortical vasculature. The obtained underlying activation profiles are closer to the activity profiles expected from electrophysiology for the type of stimulus used.

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