Marco Pizzolato1, Rutger Fick1, Timothé Boutelier2, and Rachid Deriche1
In DSC-MRI the presence of dispersion affects the estimation, via
deconvolution, of the residue function that characterizes the
perfusion in each voxel. Dispersion is described by a Vascular
Transport Function (VTF) which knowledge is essential to recover a
dispersion-free residue function.
State-of-the-art techniques aim at characterizing the VTF but assume
a specific shape for it, which in reality is unknown. We propose to
estimate the residue function without assumptions by means of
Dispersion-Compliant Bases (DCB). We use these results to find which
VTF model better describes the in-vivo data for each tissue type by
means of control point interpolation approaches.