Roland Krug1, Andrew Lai1, Lorenzo Nardo1, Luca Facchetti1, Misung Han1, Galateia Kazakia1, and Julio Carballido-Gamio1
MRI is currently the only modality to assess
trabecular bone structure with high-resolution in the proximal femur in-vivo.
We have optimized image acquisition and image analysis techniques to assess
microstructural bone parameters in HIV-infected individuals compared to healthy
controls. We have found significant differences in the femoral head, neck and
trochanteric regions between patients and controls. We conclude that MRI can be
an important tool to assess bone structure in the central skeleton at important
fracture sites such as the proximal femur with very high resolution.