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Abstract #0678

High-Resolution MRI to Assess Trabecular Bone Microstructure in the Proximal Femur of HIV-Infected Men

Roland Krug1, Andrew Lai1, Lorenzo Nardo1, Luca Facchetti1, Misung Han1, Galateia Kazakia1, and Julio Carballido-Gamio1

1University of California, UCSF, San Francisco, CA, United States

MRI is currently the only modality to assess trabecular bone structure with high-resolution in the proximal femur in-vivo. We have optimized image acquisition and image analysis techniques to assess microstructural bone parameters in HIV-infected individuals compared to healthy controls. We have found significant differences in the femoral head, neck and trochanteric regions between patients and controls. We conclude that MRI can be an important tool to assess bone structure in the central skeleton at important fracture sites such as the proximal femur with very high resolution.

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