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Abstract #0679

Age-related loss of bound water in human trabecular bone

Mathilde Granke1, Kuniko Hunter2, Sasidhar Uppuganti1, Jeffry S Nyman1,3, and Mark D Does1

1Vanderbilt University, Nashville, TN, United States, 2Rensselaer Polytechnic Institute, Troy, NY, United States, 3VA Tennessee Valley Healthcare System, Nashville, TN, United States

1H NMR- derived bound water measurements in cadaveric human trabecular bone are sensitive to age-related changes in the quality of bone tissue, and therefore could be predictive of fracture risk in trabecular sites prone to fracture.

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