Abstract #0743

Utilizing the improved receive sensitivity from high permittivity materials for SNR-challenged applications of ultrahigh b-factor diffusion-weighted spectroscopy at 7 Tesla

Carson Ingo¹, Wyger M. Brink¹, Andrew G. Webb¹, and Itamar Ronen¹

¹C.J. Gorter Center for High Field MRI, Department of Radiology, Leiden University Medical Center, Leiden, Netherlands

Diffusion-weighted 7T MR spectroscopy in white matter regions of the brain using ultrahigh b-factors have established that intracellular metabolites exhibit non-Gaussian diffusion. Such measurements using b-factors well above 10,000 s/mm² have inherently low SNR, and so it is crucial to optimize B₁ sensitivity to ensure reliable results. Here we show that a single high permittivity pad can increase the receive sensitivity by ~30%, resulting in potential reductions in data acquisition time of ~70%.

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