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Abstract #0744

High resolution whole-brain diffusion MRI at 7 Tesla using parallel RF transmission: how fast can we go?

Xiaoping Wu1, Nicolas Boulant2, Vincent Gras2, Jinfeng Tian1, Sebastian Schmitter1, Pierre-Francois Van de Moortele1, and Kamil Ugurbil1

1CMRR, Radiology, University of Minnesota, Minneapolis, MN, United States, 2CEA/NeuroSpin, Saclay, France

The Human Connectome Project (HCP) in the WU-Minn consortium aims to acquire multiband (MB)-accelerated whole brain diffusion MRI (dMRI). Although shown advantageous over 3T dMRI in inferring connectivity, the 7T acquisition suffers from transmit B1 inhomogeneity and SAR, the latter currently limiting the slice acceleration to an MB factor of 2 (MB=2). In this study, we investigated numerically the highest possible slice acceleration for 7T HCP-type dMRI acquisition with ~1-mm isotropic resolutions. Our results suggest that parallel RF transmission can be used to enable MB=4 while improving flip angle homogeneity across the whole brain as compared to a CP mode.

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