Abstract #0748

Magnetic resonance imaging of low-grade and high-grade gliomas at 7 Tesla

Bixia Chen^1,2, Philipp Dammann^1,2, Stefan Maderwald¹, Soeren Johst¹, Tobias Schoemberg^1,2, Lale Umutlu^1,3, Harald H. Quick^1,4, Mark Edward Ladd^1,5, Ulrich Sure², and Karsten Henning Wrede^1,2

¹Erwin L. Hahn Institute for MRI, University of Duisburg-Essen, Essen, Germany, ²Department of Neurosurgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany, ³Institute of Diagnostic and Interventional Radiology and Neuroradiology, University of Duisburg-Essen, Essen, Germany, ⁴High Field and Hybrid MR Imaging, University Hospital Essen, University of Duisburg-Essen, Essen, Germany, ⁵Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany

Magnetic resonance imaging (MRI) plays a major role in diagnosis, multimodal treatment planning, and follow-up of low-grade and high-grade gliomas. In this prospective study, 24 patients were intra-individually examined at 3 Tesla (T) and 7T utilizing MPRAGE, T₂ TSE, T₂ FLAIR, and SWI sequences. Image evaluation had special focus on intra-tumoral structures, vascularization, intra-lesional hemorrhages, and contrast uptake. At 7T, intra-tumoral structures were depicted in excellent image quality. Especially SWI was superior at 7T compared to 3T and revealed microhemorrhages and vascularization patterns correlating with histopathology, possibly providing an additional imaging predictor for future grading of malignant gliomas.

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