Abstract #0749

High-resolution placental MR angiography using a nanoparticle contrast agent

Ketan Ghaghada¹, Zbigniew Starosolski¹, Igor Stupin¹, Saakshi Bhayana¹, Haijun Gao², Rohan Bhavane¹, Chandresh Patel¹, Robia Pautler³, Chandrasekhar Yallampalli², and Ananth Annapragada¹

¹Pediatric Radiology, Texas Children's Hospital, Houston, TX, United States, ²Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX, United States, ³Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, United States

Non-invasive imaging of maternal and placental vasculature in rodent species is of interest to the pre-clinical study of clinically-relevant placental pathologies. In this work, we evaluated the utility of high-resolution contrast-enhanced MR angiography using a placental non-permeable, long circulating liposomal-Gd nanoparticle contrast agent in a pregnant rat model.

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