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Abstract #0749

High-resolution placental MR angiography using a nanoparticle contrast agent

Ketan Ghaghada1, Zbigniew Starosolski1, Igor Stupin1, Saakshi Bhayana1, Haijun Gao2, Rohan Bhavane1, Chandresh Patel1, Robia Pautler3, Chandrasekhar Yallampalli2, and Ananth Annapragada1

1Pediatric Radiology, Texas Children's Hospital, Houston, TX, United States, 2Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX, United States, 3Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, United States

Non-invasive imaging of maternal and placental vasculature in rodent species is of interest to the pre-clinical study of clinically-relevant placental pathologies. In this work, we evaluated the utility of high-resolution contrast-enhanced MR angiography using a placental non-permeable, long circulating liposomal-Gd nanoparticle contrast agent in a pregnant rat model.

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