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Abstract #0754

Assessment of  passive muscle elongation using DTI: Correlation between fiber length and diffusion coefficients

Valentina Mazzoli1,2,3, Jos Oudeman1, Marco A Marra3, Klaas Nicolay2, Nico Verdonschot3, Andre M Sprengers3, Martijn Froeling4, Aart J Nederveen1, and Gustav J Strijkers5

1Department of Radiology, Academic Medical Center, Amsterdam, Netherlands, 2Biomedical NMR, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands, 3Orthopaedic Research Lab, Radboud University Medical Center, Nijmegen, Netherlands, 4Department of Radiology, University Medical Center, Utrecht, Netherlands, 5Biomedical Engineering and Physics, Academic Medical Center, Amsterdam, Netherlands

The aim of this study is to explore Diffusion Tensor Imaging in the assessment of passive muscle elongation. We investigated two dorsiflexor and two plantarflexor muscles of the lower leg with the foot in dorsiflexion, neutral and plantarflexion position. Significant negative correlation was found between changes in fiberlength caused by passive muscle lengthening and radial diffusivity for all muscles. Furthermore the rate of change in radial diffusivity was compatible with a cylindrical model with constant volume. These findings give more insight into diffusion mechanisms in skeletal muscles and are highly relevant for biomechanical models.

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