Abstract #0770

Perivascular Space Analysis in Non-lesional Epilepsy: Exploring a Biomarker for Epilepsy

Rebecca Emily Feldman¹, Jack Rutland², Bradley Neil Delman³, Jiyeoun Yoo⁴, Madeline Cara Fields⁴, Lara Vanessa Marcuse⁴, and Priti Balchandani¹

¹Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ²Wake Forest University, Winston-Salem, NC, United States, ³Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ⁴Neurology, Mount Sinai Hospital, New York, NY, United States

Epilepsy is a chronic condition, affecting approximately 150,000 people in the United States. 7T MRI facilitates the visualization of the brain with unprecedented resolution and contrast. Perivascular spaces (PVS) have been reported in previous work but with uncertain significance. However, due to the increased resolution enabled at 7T, PVSs are detected with increasing frequency, both in healthy volunteers and in epilepsy patients. We investigated the symmetry in the distribution of PVSs in the brains of non-lesional epilepsy patients.

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