Abstract #0775

7T MRI detection of epileptogenic foci in previously non-lesional patients with focal epilepsy

Rebecca Emily Feldman¹, Bradley Neil Delman², Hadrien A Dyvorne¹, Jiyeoun Yoo³, Madeline Cara Fields³, Lara Vanessa Marcuse³, and Priti Balchandani¹

¹Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ²Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ³Neurology, Mount Sinai Hospital, New York, NY, United States

Epilepsy affects over 150,000 people in the United States. Thirty percent of epilepsy is refractory to pharmacotherapy, and in these cases surgery may be curative. There are focal epileptogenic lesions, amenable to surgery, which are not visualized by current imaging protocols. 7T MRI scanners may increase the conspicuity of epileptogenic lesions and provide more accurate delineation of lesion boundaries. Reported are the results for a patient study, with comparison to healthy controls, to assess the value of 7T imaging to reveal subtle abnormalities acting as epileptogenic foci in patients with focal epilepsy who have non-lesional diagnostic MRI scans.

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