Meeting Banner
Abstract #0793

Challenges in solving the two-compartment free-water diffusion MRI model

Ørjan Bergmann1,2, Carl-Fredrik Westin1, and Ofer Pasternak1

1Dept of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States, 2Norwegian Competency Center for MS, Haukeland University Hospital, Bergen, Norway

In this work we explore the solution space of the two-compartment free-water problem under different noise levels. Based on the shape of the solution space we show that solving this model in an intuitive and straightforward manner may result in solutions which are sensitive to noise, and that are biased towards neglecting the free-water component. Although multi-shell techniques improve the situation we show that more advanced methods are required to further stabilize the solution.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords