Moritz Schneider1, Thomas Gaaß1,2, Julien Dinkel1,2, Michael Ingrisch1, Maximilian F Reiser1, and Olaf Dietrich1
1Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital Munich, Munich, Germany, 2Comprehensive Pneumology Center, German Center for Lung Research, Munich, Germany
In this study we
present intravoxel incoherent motion (IVIM) measurements in a flow phantom consisting
of a 3-dimensional capillary network made from melt-spun, sacrificial sugar
structures embedded in a synthetic resin. IVIM parameters were determined at varying
water flow rates. The pseudodiffusion D* (associated with flow velocity) as
well as the product D*×f (which constitutes a measure of flow) show proportionality
to the applied flow rates. These results demonstrate that the presented flow
phantom is ideal to assess the applicability of IVIM measurements and influence
factors such as flow rates, capillary diameter or acquisition parameters.
