Abstract #0920

Intravoxel Incoherent Motion MRI in a 3-Dimensional Microvascular Flow Phantom

Moritz Schneider¹, Thomas Gaaß^1,2, Julien Dinkel^1,2, Michael Ingrisch¹, Maximilian F Reiser¹, and Olaf Dietrich¹

¹Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital Munich, Munich, Germany, ²Comprehensive Pneumology Center, German Center for Lung Research, Munich, Germany

In this study we present intravoxel incoherent motion (IVIM) measurements in a flow phantom consisting of a 3-dimensional capillary network made from melt-spun, sacrificial sugar structures embedded in a synthetic resin. IVIM parameters were determined at varying water flow rates. The pseudodiffusion D* (associated with flow velocity) as well as the product D*×f (which constitutes a measure of flow) show proportionality to the applied flow rates. These results demonstrate that the presented flow phantom is ideal to assess the applicability of IVIM measurements and influence factors such as flow rates, capillary diameter or acquisition parameters.

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