Abstract #0941

Ultra-fast gradient echo EPI with controlled aliasing at 3T: simultaneous multi-slice vs. 3D-EPI

Rüdiger Stirnberg¹, Willem Huijbers¹, Benedikt A. Poser², and Tony Stöcker^1,3

¹German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany, ²Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands, ³Department of Physics and Astronomy, University of Bonn, Bonn, Germany

We conducted a feasibility study to compare state-of-the-art simultaneous multi-slice EPI vs. segmented 3D-EPI – both utilizing equivalent undersampling techniques for controlled aliasing – optimized for ultra-fast whole-brain fMRI at 3T. We compared temporal signal-to-noise ratio, sensitivity per unit scan time and temporal whole-brain spectra of 8 minutes time-series. While both fast sequences are well-suited to separate physiological from BOLD signal, the 3D-EPI sequence achieves greater sensitivity and signal-to-noise ratio throughout the brain using whole-brain protocols matched for identical TR.

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