Abstract #0944

Blood volume fMRI with 3D-EPI-VASO: any benefits over SMS-VASO?

Laurentius Huber¹, Dimo Ivanov², Sean Marrett¹, Puja Panwar¹, Kamil Uludag², Peter A Bandettini¹, and Benedikt A Poser²

¹Section of Functional Imaging Methods, National Institute of Mental Health, Bethesda, MD, United States, ²MBIC, Maastricht University, Maastricht, Netherlands

Cerebral blood volume (CBV) fMRI has the potential to overcome known limitations of BOLD fMRI with respect to spatial specificity and quantifiability of mapping brain activity. To overcome the coverage limitations of conventional CBV mapping with VASO, a novel VASO method with 3D-EPI readout was developed. This new approach is compared to BOLD fMRI and VASO with simultaneous multi-slice EPI readout. We provide evidence for a high sensitivity and improved specificity of 3D-EPI VASO compared to conventional BOLD fMRI. We conclude that because of its superior resolution in slice-direction, 3D-EPI VASO may play an important role in high-resolution fMRI.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.