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Abstract #0975

Comparative Study of Modelling DW-MRI Data From High-grade Serous Carcinomas and Clear Cell Carcinomas

Feng Wang1, Jianyu Liu1, Yan Zhou1, and Lizhi Xie2

1Radiology Department of Peking University Third Hospital, Beijing, China, People's Republic of, 2GE Healthcare, MR Research China, Beijing, Beijing, China, People's Republic of

The aim of this study was to assess if the histogram analysis of mono-exponential, bi-exponential and stretched exponential models of diffusion-weighted MRI (DW-MRI) parameters can differentiate two common subtypes of ovarian epithelial cancer: high-grade serous carcinomas (HGSCs) and clear cell carcinomas(CCCs). Based on an entire-tumour measurement, the following histogram parameters were derived from ADC, D, D*, F, DDC and α maps, respectively: the mean of the whole tumor, the 10th percentile and the mean of the top 10 percent. We concluded that ADC, D, F, DDC and α have showed good diagnostic performance by analyzing these data.

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