Abstract #0975

Comparative Study of Modelling DW-MRI Data From High-grade Serous Carcinomas and Clear Cell Carcinomas

Feng Wang¹, Jianyu Liu¹, Yan Zhou¹, and Lizhi Xie²

¹Radiology Department of Peking University Third Hospital, Beijing, China, People's Republic of, ²GE Healthcare, MR Research China, Beijing, Beijing, China, People's Republic of

The aim of this study was to assess if the histogram analysis of mono-exponential, bi-exponential and stretched exponential models of diffusion-weighted MRI (DW-MRI) parameters can differentiate two common subtypes of ovarian epithelial cancer: high-grade serous carcinomas (HGSCs) and clear cell carcinomas(CCCs). Based on an entire-tumour measurement, the following histogram parameters were derived from ADC, D, D*, F, DDC and α maps, respectively: the mean of the whole tumor, the 10th percentile and the mean of the top 10 percent. We concluded that ADC, D, F, DDC and α have showed good diagnostic performance by analyzing these data.

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