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Abstract #0992

Left ventricular (LV) volume and rate of volume change (dV/dt) during the early and late filling periods evaluated from respiratory triggered, high frame rate cine SSFP as markers of LV diastolic function: Direct correlation with Echocardiography

Jiming Zhang1, Benjamin Y Cheong1, Jie Chen1, Amol Pednekar2, Claudio Arena1, Melissa L Andrews1, and Raja Muthupillai1

1Diagnostic and Interventional Radiology, CHI St Luke's Health, Houston, TX, United States, 2Phillips Healthcare, Cleveland, OH, United States

LV chamber volumes measured using MR cine SSFP imaging and trans-mitral flow velocities measured with echo are considered de facto standards for evaluating LV systolic and diastolic function respectively. Our results show that the relative change in LV volume as well as peak LV volume-rate between the early and late filling periods of the cardiac cycle as measured from high-frame rate cine SSFP imaging, correlate well with conventional echo-based diastolic function index (E/A ratio). The results from the study suggest that a free-breathing, high frame rate MR cine SSFP imaging approach can evaluate both systolic and diastolic function from a single LV volume data-set.

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