Abstract #0994

Reduced field-of-view 3D stack-of-spirals perfusion imaging with high spatiotemporal resolution

Yang Yang¹, Li Zhao², Xiao Chen³, Kelvin Chow⁴, Peter W. Shaw⁴, Jorge A. Gonzalez⁴, Frederick H. Epstein^1,5, Craig H. Meyer^1,5, Christopher M. Kramer^4,5, and Michael Salerno^1,4,5

¹Biomedical Engineering, University of Virginia, Charlottesville, VA, United States, ²Radiology, Beth Israel Deaconess Medical Center & Harvard Medical, Boston, MA, United States, ³Medical Imaging Technologies, Siemens Healthcare, Princeton, NJ, United States, ⁴Medicine, University of Virginia, Charlottesville, VA, United States, ⁵Radiology, University of Virginia, Charlottesville, VA, United States

3D CMR perfusion imaging enables whole ventricular coverage at the same cardiac cycle permitting quantification of ischemic burden of patients being evaluated for coronary artery disease. Current 3D techniques have limited spatial-temporal resolution. We developed an efficient outer-volume suppressed 3D Stack-of-Spiral perfusion sequence with motion-guided compressed sensing reconstruction which can acquire 20 partitions with 2 mm in-plane and 4 mm through-plane resolution with a temporal foot print of 180 ms. A pilot study of 10 subjects using this technique demonstrates clinically acceptable image quality.

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