Abstract #0995

Multi-center study of whole-heart dynamic 3-dimensional cardiac magnetic resonance perfusion imaging for the detection of coronary artery disease – analysis of diagnostic performance in women

Sandra Hamada¹, Alexander Gotschy^2,3, Lukas Wissmann³, Sebastian Kozerke³, Cosima Jahnke⁴, Ingo Paetsch⁴, Rolf Gebker⁵, Nikolaus Marx⁶, Hatem Alkadhi¹, and Manka Robert^1,7

¹Institue of Diagnostic and Interventional Radiology, University Hospital Zurich, Zurich, Switzerland, ²Department and Policlinic of Internal Medicine, University Hospital Zurich, Zurich, Switzerland, ³Institue for Biomecical Engineering, University and ETH Zurich, Zurich, Switzerland, ⁴University Heart Center Leipzig, Leipzig, Germany, ⁵German Heart Institute Berlin, Berlin, Germany, ⁶Department of Cardiology, Pneumology, Angiology and Intensive Care Medicine, University Hospital RWTH Aachen, Aachen, Germany, ⁷Department of Cardiology, University Heart Center, Universitiy Hospital Zurich, Zurich, Switzerland

Coronary heart disease accounts for a large amount of morbidity and mortality in women. To contribute to evidence for non-invasive testing in women, this study compares diagnostic performance of whole heart dynamic 3D myocardial first-pass perfusion stress imaging in female and male with findings in coronary angiography. 61 female and 139 male with suspected and known coronary artery disease were enrolled and a whole heart dynamic 3D-CMR first-pass perfusion imaging was performed at rest and at stress. Whole heart dynamic 3D-CMR perfusion imaging shows high sensitivity, specificity and diagnostic accuracy in women and men and therefore seems to be a suitable testing tool for myocardial ischemia in women and men.

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