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Abstract #0995

Multi-center study of whole-heart dynamic 3-dimensional cardiac magnetic resonance perfusion imaging for the detection of coronary artery disease – analysis of diagnostic performance in women

Sandra Hamada1, Alexander Gotschy2,3, Lukas Wissmann3, Sebastian Kozerke3, Cosima Jahnke4, Ingo Paetsch4, Rolf Gebker5, Nikolaus Marx6, Hatem Alkadhi1, and Manka Robert1,7

1Institue of Diagnostic and Interventional Radiology, University Hospital Zurich, Zurich, Switzerland, 2Department and Policlinic of Internal Medicine, University Hospital Zurich, Zurich, Switzerland, 3Institue for Biomecical Engineering, University and ETH Zurich, Zurich, Switzerland, 4University Heart Center Leipzig, Leipzig, Germany, 5German Heart Institute Berlin, Berlin, Germany, 6Department of Cardiology, Pneumology, Angiology and Intensive Care Medicine, University Hospital RWTH Aachen, Aachen, Germany, 7Department of Cardiology, University Heart Center, Universitiy Hospital Zurich, Zurich, Switzerland

Coronary heart disease accounts for a large amount of morbidity and mortality in women. To contribute to evidence for non-invasive testing in women, this study compares diagnostic performance of whole heart dynamic 3D myocardial first-pass perfusion stress imaging in female and male with findings in coronary angiography. 61 female and 139 male with suspected and known coronary artery disease were enrolled and a whole heart dynamic 3D-CMR first-pass perfusion imaging was performed at rest and at stress. Whole heart dynamic 3D-CMR perfusion imaging shows high sensitivity, specificity and diagnostic accuracy in women and men and therefore seems to be a suitable testing tool for myocardial ischemia in women and men.

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