Abstract #1064

Multi-contrast joint intra- and extracranial artery wall imaging – a feasibility study

Lei Zhang¹, Jun Wu², Lijie Ren³, Tingting Wang², Xin Liu¹, and Yiu-Cho Chung¹

¹Paul C. Lauterbur Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academic of Sciences, Shenzhen, China, People's Republic of, ²Neurology, Peking University Shenzhen Hospital, Shenzhen, China, People's Republic of, ³Neurology, Shenzhen Second People’s Hospital, Shenzhen, China, People's Republic of

In this study, we evaluated multi-contrast three dimensional (3D) high resolution black blood vessel wall imaging technique for joint intra- and extracranial artery wall imaging in 8 stroke patients. The new techniques covered both the intra- and extracranial segments in one scan. T1w, T2w scans were performed. MPRAGE was included when hemmorrhage was suspected. 8 plaques were identified. Two of them had high signal in all three sequences, suggestive of intraplaque hemorrhage. The 3D multi-contrast large coverage black blood techniques would be a promising tool to the study on the association between atherosclerotic plaques and ischemic stroke.

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