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Abstract #1077

Cardiac and Respiratory Self-Gated 4D Multi-Phase Steady-State Imaging with Ferumoxytol Contrast (MUSIC)

Fei Han1, Ziwu Zhou1, Takegawa Yoshida1, Kim-Lien Nguyen1,2, Paul J Finn1, and Peng Hu1

1Radiology, University of California, Los Angeles, Los Angeles, CA, United States, 2Division of Cardiology, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA, United States

We proposed a cardiac and respiratory self-gated, 4D multi-phase steady-state imaging with contrast (MUSIC) technique for detailed evaluation of cardiovascular anatomies. A rotating cartesian k-space sampling pattern was designed that integrates frequently sampled k-space centerline as self-gating signal and allows retrospective data-binning based on derived motion signal. Phantom and in-vivo results on 7 clinical indicated pediatric CHD patients show that the proposed self-gated MUSIC could potentially eliminates the need of external physiological signal for motion gating, has increased scan efficiency while maintaining or exceeding the image quality of the original MUSIC.

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