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Abstract #1108

Volume-Parcellated Quantitative Susceptibility Mapping

Casey Anderson1, Andrew Nencka2, Tugan Muftuler3, Kathleen Schmainda2, and Kevin Koch2

1Biophysics, Medical College of Wisconsin, Milwaukee, WI, United States, 2Radiology, Medical College of Wisconsin, Milwaukee, WI, United States, 3Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, United States

Quantitative susceptibility maps are routinely compromised by streaking artifacts. Here, we present a technique called volume-parcellated quantitative susceptibility mapping (VP-QSM), which performs independent susceptibility inversion on multiple reduced field-of-view parcels over the entire tissue field map. These parcels are combined to form a composite susceptibility map. In this algorithm, streaking artifacts are confined to individual parcels, improving the quality of the susceptibility map without a dependence on the underlying QSM inversion algorithm. In this study, VP-QSM is demonstrated on a 7T human volunteer, as well as on 30 subjects participating in sports concussion and brain cancer neuroimaging research protocols.

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