Abstract #1108

Volume-Parcellated Quantitative Susceptibility Mapping

Casey Anderson¹, Andrew Nencka², Tugan Muftuler³, Kathleen Schmainda², and Kevin Koch²

¹Biophysics, Medical College of Wisconsin, Milwaukee, WI, United States, ²Radiology, Medical College of Wisconsin, Milwaukee, WI, United States, ³Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, United States

Quantitative susceptibility maps are routinely compromised by streaking artifacts. Here, we present a technique called volume-parcellated quantitative susceptibility mapping (VP-QSM), which performs independent susceptibility inversion on multiple reduced field-of-view parcels over the entire tissue field map. These parcels are combined to form a composite susceptibility map. In this algorithm, streaking artifacts are confined to individual parcels, improving the quality of the susceptibility map without a dependence on the underlying QSM inversion algorithm. In this study, VP-QSM is demonstrated on a 7T human volunteer, as well as on 30 subjects participating in sports concussion and brain cancer neuroimaging research protocols.

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