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Abstract #1114

Quantitative susceptibility mapping of magnetic quadrupole moments

Junghun Cho1, Dong Zhou2, Pascal Spincemaille2, and Yi Wang1,2

1Biomedical Engineering, Cornell University, NEW YORK, NY, United States, 2Radiology, Weill Cornell Medical College, NEW YORK, NY, United States

In the study of quantitative susceptibility mapping, dipole approximation is widely used where the magnetic field of each voxel is approximated as dipole field. In general, higher order field such as quadrupole field also exists, especially for voxels with non-uniform subvoxel magnetization/susceptibility distributions. We modeled the magnetic field in MRI experiment up to quadrupole term and used multiple orientation measurement to acquire both the dipole (average susceptibility) and quadrupole (susceptibility distribution) contributions. The feasibility of the proposed method is demonstrated in an experimental gadolinium water phantom study.

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