Junghun Cho1, Dong Zhou2, Pascal Spincemaille2, and Yi Wang1,2
1Biomedical Engineering, Cornell University, NEW YORK, NY, United States, 2Radiology, Weill Cornell Medical College, NEW YORK, NY, United States
In the
study of quantitative susceptibility mapping, dipole approximation is widely
used where the magnetic field of each voxel is approximated as dipole field. In
general, higher order field such as quadrupole field also exists, especially
for voxels with non-uniform subvoxel magnetization/susceptibility
distributions. We modeled the magnetic field in MRI experiment up to quadrupole
term and used multiple orientation measurement to acquire both the dipole (average
susceptibility) and quadrupole (susceptibility distribution) contributions. The
feasibility of the proposed method is demonstrated in an experimental
gadolinium water phantom study.
