Abstract #1119

Clinical evaluation of ultra high field MRI for three-dimensional visualization of tumour size in uveal melanoma patients, with direct relevance to treatment planning.

Jan-Willem Beenakker¹, Teresa Ferreira¹, Karina Soemarwoto¹, Lorna Grech Fonk¹, Stijn Genders¹, Wouter Teeuwisse¹, Andrew Webb¹, and Gregorius Luyten¹

¹Leiden University Medical Centre, Leiden, Netherlands

Recent advances in ocular MRI make it possible to acquire high resolution three dimensional images of uveal melanoma in eye tumour patients, allowing a much better assessment of the maximal tumour prominence compared to conventional clinical ultrasound measurements. Nine uveal melanoma patients were examined on a 7 Tesla using a custom-built eye-coil. Eye-motion artefacts were minimized by the use of a cued-blinking protocol. For all patients the MR-images showed a slightly lower tumour prominence. For two of these patients this resulted in a substantial change in treatment planning, saving an eye that would otherwise have been removed.

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