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Abstract #1119

Clinical evaluation of ultra high field MRI for three-dimensional visualization of tumour size in uveal melanoma patients, with direct relevance to treatment planning.

Jan-Willem Beenakker1, Teresa Ferreira1, Karina Soemarwoto1, Lorna Grech Fonk1, Stijn Genders1, Wouter Teeuwisse1, Andrew Webb1, and Gregorius Luyten1

1Leiden University Medical Centre, Leiden, Netherlands

Recent advances in ocular MRI make it possible to acquire high resolution three dimensional images of uveal melanoma in eye tumour patients, allowing a much better assessment of the maximal tumour prominence compared to conventional clinical ultrasound measurements. Nine uveal melanoma patients were examined on a 7 Tesla using a custom-built eye-coil. Eye-motion artefacts were minimized by the use of a cued-blinking protocol. For all patients the MR-images showed a slightly lower tumour prominence. For two of these patients this resulted in a substantial change in treatment planning, saving an eye that would otherwise have been removed.

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