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Abstract #1118

Reconstruction and validation of T2-weighted 4D Magnetic Resonance Imaging for radiotherapy treatment planning

Zdenko van Kesteren1, Daniƫl Tekelenburg1,2, Oliver Gurney-Champion1,3, Aart Nederveen3, Eelco Lens1, Astrid van der Horst1, Aleksandra Biegun2, and Arjan Bel1

1radiotherapy, Academic Medical Centre, Amsterdam, Netherlands, 2KVI-Center for Advanced Radiation Technology, University of Groningen, Groningen, Netherlands, 3radiology, Academic Medical Centre, Amsterdam, Netherlands

We developed a respiratory-correlated 4DMRI for abdominal imaging by retrospective sorting 2D T2-weighted TSE images. Each image is assigned to a respiratory state, which is either binned in phase or the amplitude domain. The diaphragm motion per image was determined by registering the diaphragm to the begin-inhale image of a series. Per slice and per bin multiple images were acquired and we defined the intra-bin variation as the standard deviation of diaphragm positions. Amplitude binning results in lower intra-bin variation with respect to phase binning, 0.8 versus 2.4 mm respectively.

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