Abstract #1118

Reconstruction and validation of T2-weighted 4D Magnetic Resonance Imaging for radiotherapy treatment planning

Zdenko van Kesteren¹, Daniël Tekelenburg^1,2, Oliver Gurney-Champion^1,3, Aart Nederveen³, Eelco Lens¹, Astrid van der Horst¹, Aleksandra Biegun², and Arjan Bel¹

¹radiotherapy, Academic Medical Centre, Amsterdam, Netherlands, ²KVI-Center for Advanced Radiation Technology, University of Groningen, Groningen, Netherlands, ³radiology, Academic Medical Centre, Amsterdam, Netherlands

We developed a respiratory-correlated 4DMRI for abdominal imaging by retrospective sorting 2D T2-weighted TSE images. Each image is assigned to a respiratory state, which is either binned in phase or the amplitude domain. The diaphragm motion per image was determined by registering the diaphragm to the begin-inhale image of a series. Per slice and per bin multiple images were acquired and we defined the intra-bin variation as the standard deviation of diaphragm positions. Amplitude binning results in lower intra-bin variation with respect to phase binning, 0.8 versus 2.4 mm respectively.

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