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Abstract #1169

Distortion correction in diffusion weighted imaging of the brain: a quantitative comparison of four correction approaches

Ileana Hancu1, Ek Tsoon Tan1, Luca Marinelli1, Nathan White2, Dominic Holland2, Tim Sprenger3, and Jonathan Sperl3

1GE Global Research Center, Niskayuna, NY, United States, 2University of California San Diego, San Diego, CA, United States, 3GE Global Research Center, Munich, Germany

The performance of four distortion correction algorithms was investigated in a cohort of normal volunteers. While all approaches reduced distortion, it was found that the reversed polarity gradient methods were inherently better than registration or B0-mapping approaches. It was likely that the limited degrees of freedom of the registration approach could not account for localized magnetic field inhomogeneity. The extrapolation of B0 maps in the distorted EPI space introduced errors that decreased the overall performance of the B0-mapping method.

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