Abstract #1169

Distortion correction in diffusion weighted imaging of the brain: a quantitative comparison of four correction approaches

Ileana Hancu¹, Ek Tsoon Tan¹, Luca Marinelli¹, Nathan White², Dominic Holland², Tim Sprenger³, and Jonathan Sperl³

¹GE Global Research Center, Niskayuna, NY, United States, ²University of California San Diego, San Diego, CA, United States, ³GE Global Research Center, Munich, Germany

The performance of four distortion correction algorithms was investigated in a cohort of normal volunteers. While all approaches reduced distortion, it was found that the reversed polarity gradient methods were inherently better than registration or B0-mapping approaches. It was likely that the limited degrees of freedom of the registration approach could not account for localized magnetic field inhomogeneity. The extrapolation of B0 maps in the distorted EPI space introduced errors that decreased the overall performance of the B0-mapping method.

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