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Abstract #1171

The Neural Basis of Visual Field Asymmetry in Human Visual System by Functional MRI

Caitlin O'Connell1, Leon Ho2,3, Matthew Murphy2, Yolandi van der Merwe1,2, Ian Conner1,2, Gadi Wollstein1,2, Joel Schuman1,2, Rakie Cham1, and Kevin Chan1,2

1Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States, 2UPMC Eye Center, Eye and Ear Institute, Ophthalmology and Visual Science Research Center, Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, United States, 3Department of Electrical and Electronic Engineering, The University of Hong Kong, Pokfulam, Hong Kong

Human visual performance has been observed to exhibit superiority in the lower visual field and horizontal meridian compared to the upper visual field and vertical meridian, respectively, in response to many classes of stimuli, but the underlying neural mechanisms remain unclear. This study determines if processing of visual information is dependent on the location of stimuli in the visual field using functional MRI. The results show stronger brain responses and larger activation volumes upon flickering visual stimulation to the lower hemifield compared to upper hemifield, while only the activation size differed between visual presentations to the horizontal and vertical meridians.

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