Abstract #1175

The cerebrovascular response to a single session of exercise

Jessica Steventon¹, Catherine Foster¹, Daniel Helme², Monica Busse³, and Kevin Murphy¹

¹CUBRIC, Cardiff University, Cardiff, United Kingdom, ²School of Medicine, Cardiff University, Cardiff, United Kingdom, ³School of Healthcare Sciences, Cardiff University, Cardiff, United Kingdom

Here we examine the acute effects of a single exercise session on cerebrovasculature using a multi-TI arterial spin labelling (ASL) sequence to measure cerebral blood flow (CBF), and a dual-echo ASL sequence with hypercapnia to measure cerebrovascular reactivity (CVR). We show that contrary to previous smaller studies, 20-minutes of aerobic exercise does not affect CBF or CVR in the 60-minute period after exercise. Despite this, changes in CBF after exercise were related to individually-determined systemic physiological changes associated with exercise intensity, informing on moderators of cerebral autoregulation.

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