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Abstract #1185

Cervical spondyloarthropathy due to the dialysis-related amyloidosis: magnetic resonance imaging findings

Hale Turnaoglu1, Kemal Murat Haberal1, Ozlem Isiksacan Ozen2, and Ahmet Muhtesem Agildere1

1Radiology, Baskent University, Faculty of Medicine, Ankara, Turkey, 2Pathology, Baskent University, Faculty of Medicine, Ankara, Turkey

Dialysis-related amyloidosis that occurs secondarily to the deposition of amyloid fibrils containing beta-2-microglobulin, is a type of amyloidosis affecting patients undergoing long-term hemodialysis. It involves the osteoarticular system predominantly. Destructive spondyloarthropathy, which frequently involves the cervical spine, have been reported only sporadically. CT is the best modality for detecting osseous erosion or small areas of osteolysis in cortical bone. MRI shows the extent and distribution of osseous, articular, spinal cord and soft-tissue involvement and indicates amyloid deposits in the intervertebral disk, synovium of apophyseal joints, and ligaments. The gold standart of the diagnosis is the histological identification of beta-2-microglobulin.

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