Abstract #1206

Gray matter networks in the mouse brain

Marco Pagani^1,2, Angelo Bifone¹, and Alessandro Gozzi¹

¹Istituto Italiano di Tecnologia, Rovereto, Italy, ²Center for Mind and Brain Sciences, Rovereto, Italy

Structural covariance MRI (scMRI) has highlighted robust gray matter networks encompassing known neuroanatomical systems of the human brain. The application of scMRI in the mouse can provide insights on the elusive neurobiological determinants underlying the emergence of this phenomenon. We show that the mouse brain contains robust inter-hemispheric anatomical covariance networks recapitulating anatomical features observed in humans. Our findings pave the way to the use of mouse genetics to investigate the biological underpinnings of scMRI networks and their aberration in brain disorders.

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