Abstract #1215

Volumetric analysis of structural brain changes in acute and sub-acute mild traumatic brain injury

Tianhao Zhang¹, Sumit Niogi², John A. Tsiouris², Luca Marinelli³, and Teena Shetty⁴

¹GE Healthcare, Waukesha, WI, United States, ²Weill Cornell Medical Center, New York, NY, United States, ³GE Global Research, Niskayuna, NY, United States, ⁴Hospital for Special Surgery, New York, NY, United States

Mild traumatic brain injury (mTBI) is a heterogeneous disease with a variety of symptoms associated with brain function alterations after the trauma. There is still limited understanding of the relationship between physiological and structural changes and recovery rate. In this work, we aim to identify structural brain changes in a mTBI population at 4 time points. The analysis is in two folds: 1) correlation analysis between brain volumes and clinical scores; and 2) longitudinal analysis across different encounters. The results revealed significant brain volume changes over time, and at 3 months post-injury, volumes demonstrated significant negative correlations with clinical scores.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.