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Abstract #1228

Direct visualization human pedunculopontine nucleus: validation and new coordinate establishing

Fei Cong1, Jiawei Wang2, Zhangyan Yang1, Bo Wang1, Yuqing Zhang2, and Yan Zhuo1

1Institute of Biophysics, Chinese Academy of Science, Beijing, China, People's Republic of, 2Functional neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China, People's Republic of

The pedunculopontine nucleus (PPN), as a potential Deep brain stimulation (DBS) target for the patients to improve gait and posture. Until now, only a few results of the location of PPN has been published. In this study, 7T ultra-high field MR system and high resolution MP2RAGE sequence were used to locate the PPN by a direct view, and a new coordinate designed for PPN location was introduced and test. The boundary of PPN was display and a more consistency coordinate used for localizing PPN was presented.

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