Abstract #1228

Direct visualization human pedunculopontine nucleus: validation and new coordinate establishing

Fei Cong¹, Jiawei Wang², Zhangyan Yang¹, Bo Wang¹, Yuqing Zhang², and Yan Zhuo¹

¹Institute of Biophysics, Chinese Academy of Science, Beijing, China, People's Republic of, ²Functional neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China, People's Republic of

The pedunculopontine nucleus (PPN), as a potential Deep brain stimulation (DBS) target for the patients to improve gait and posture. Until now, only a few results of the location of PPN has been published. In this study, 7T ultra-high field MR system and high resolution MP2RAGE sequence were used to locate the PPN by a direct view, and a new coordinate designed for PPN location was introduced and test. The boundary of PPN was display and a more consistency coordinate used for localizing PPN was presented.

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