Abstract #1231

γ-aminobutyric acid spectroscopy of the thalamus in diabetic neuropathy

Iain D Wilkinson¹, Pillai Shillo¹, Marni Greig¹, Solomon Tesfaye¹, Richard A Edden², and Dinesh Selvarajah¹

¹Academic Radiology, University of Sheffield, Sheffield, United Kingdom, ²Kennedy Krieger Institute, Baltimore, MA, United States

The sensory system is affected in diabetic neuropathy (DN), a common ailment associated with diabetes mellitus. The thalamus is part of the brain’s sensory pathway. This study applies MEGA-PRESS to assess thalamic GABA in-vivo in patients with and without DN. Differences in GABA/H20 ratios were identified between those with and without DN, demonstrating potential differences in the neuronal inhibitory status of the thalamus.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.