Associations between Brain Microstructural and Motor Severity of Parkinsonian Symptoms in Elderly Parkinson Diseases
MohammadHadi Aarabi1, Farzaneh Rahmani1, Ahmad Shojaei2, and Hamidreza Safabakhsh2
1Students'Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran, 2Basir Eye Health Research Center, Tehran, Iran., Tehran, Iran
Disease (PD) is a progressive neurodegenerative disorder assumed to involve
different areas of CNS and PNS. Thus, Diffusion Tensor Imaging (DTI) is used to
examine the areas engaged in PD neurodegeneration. We
studied the relationship between local connectome alterations obtained by
connectometry approach and motor severity of elderly PD as measured with
Unified Parkinson's disease 3. Our findings demonstrate the fornix and cingulium fibers in limbic
system have association with motor severity in elderly PD patients in onset.
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