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Abstract #1253

Conformity between Brain structures and Neuropsychological tests in Methamphetamine Abusers

Artit Rodkong1, Nuttawadee Intachai1, Suwit Saekho1,2, Apinun Aramrattana3, Kanok Uttawichai4, Mekkla Thomson5, Bangorn Sirirojn6, Daralak Thavornprasit6, Sineenart Taejaroenkul6, Kamolrawee Sintupat6, Victor Valcour7, Robert Paul8, and Napapon Sailasuta9

1Radiological Technology, Chiang Mai University, Chiang Mai, Thailand, 2Biomedical Engineering Center, Chiang Mai University, Chiang Mai, Thailand, 3Family Medicine, Chiang Mai University, Chiang Mai, Thailand, 4Thanyarak Hospital, Chiang Mai, Thailand, 5Westat, Rockville, MD, United States, 6Research Institute for Health Sciences, Chiang Mai, Thailand, 7Neurology, University of California, San Francisco, San Francisco, CA, United States, 8Psychology, University of Missouri, St. Louis, MO, United States, 9Huntington Medical Research Institute, Pasadena, CA, United States

Magnetic resonance imaging (MRI) studies show evidence of brain alteration in Methamphetamine (MA) users. We compare brain structures including gray matter (GM), white matter (WM) and cortical thickness between MA abusers and Healthy control (HC) group, and explore relationship between brain structures and neuropsychological performance (NP) in MA compared with HC. The results demonstrated that MA group revealed poorer cognitive function and reduced volumetrics in critical brain regions that underlie cognitive performance compared to that of the HC group.

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