Abstract #1306

Investigating the Correlation between Cognitive Fatigue and Brain Iron Deposition in Basal Ganglia in Multiple Sclerosis

Sarah Wood¹, Emilyrose Havrilla^1,2, Ekaterina Dobryakova³, Zhiguo Jiang⁴, and Bing Yao^1,5

¹Rocco Ortenzio Neuroimaging Center, Kessler Founadation, West Orange, NJ, United States, ²Department of Psychology, Montclair State University, Montclair, NJ, United States, ³Traumatic Brain Injury Laboratory, Kessler Founadation, West Orange, NJ, United States, ⁴Human Performance Engineering Laboratory, Kessler Founadation, West Orange, NJ, United States, ⁵Department of Physical Medicine & Rehabilitation, Rutgers, the State University of New Jersey, Newark, NJ, United States

Basal ganglia play important roles in cognitive fatigue, which is one of the most common symptoms in multiple sclerosis. This study examined the correlation between brain iron concentration measured by MR susceptibility contrast imaging in the basal ganglia and the severity of fatigue in the individuals with multiple sclerosis.

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