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Abstract #1320

Volume differences on quantitative susceptibility map and T2-weighted image of multiple sclerosis lesions at different disease stages and indication for iron activity

Yan Zhang1,2, Dong Zhou2, Ajay Gupta2, Susan A. Gauthier3, and Yi Wang2

1Radiology, Tongji hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China, People's Republic of, 2Radiology, Weill Cornell Medical College, New York, NY, United States, 3Neurology, Weill Cornell Medical College, New York, NY, United States

In this study, we examed different multiple sclerosis (MS) lesion patterns using quantitative susceptibility map (QSM) and compared lesion volumes on T2-weighted (T2w) and QSM images at different lesion stages. The relative lesion QSM/T2w volume increases over 1 year of the lesion onset indicates the participation of iron in chronic active lesions.

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