Abstract #1345

Can dynamic contrast enhanced MR perfusion metrics accurately discriminate different grades of Gliomas?

Jitender Saini ¹, Pradeep Kumar Gupta², Prativa Sahoo³, Rana Patir⁴, Sandeep Vaishya⁵, Arun Kumar Gupta¹, Amey Savarderkar⁶, and Rakesh Kumar Gupta²

¹Neuroimaging & Interventional Radiology, National Institute of Mental Health and Neurosciences, Bangalore, India, ²Radiology and Imaging, Fortis Memorial Research Institute, Gurgaon, India, ³Healthcare, Philips India ltd, Bangalore, India, ⁴Neuorsurgury, Fortis Memorial Research Institute, Gurgaon, India, ⁵Neuorsurgury, Fortis Memorial Research Institute, Lucknow, India, ⁶Neuorsurgury, National Institute of Mental Health and Neurosciences, Bangalore, India

Dynamic contrast enhanced MRI perfusion is a useful technique for assessment of glioma grading. This technique has been used in the past for discrimination of low from high grade gliomas. This study investigates the ability of DCE perfusion MRI to discriminate Grade II from Grade III and Grade III from Grade IV gliomas. Various DCE pharmacokinetic parameters were also analysed for their ability to distinguish the various grades of gliomas.

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