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Abstract #1357

Contrast-Enhanced Synthetic MRI for the Detection of Brain Metastases: Comparison Between Synthetic T1-weighted Inversion-recovery Image, Synthetic T1-weighted Image, and Conventional T1-weighted Inversion-recovery Fast Spin-Echo Image.

Misaki Nakazawa1,2, Akifumi Hagiwara2,3, Masaaki Hori2, Christina Andica2, Koji Kamagata2, Hideo Kawasaki2, Nao Takano2, Shuji Sato2, Nozomi Hamasaki2, Kouhei Tsuruta1,2, Sho Murata1,2, Ryo Ueda1,2, Shigeki Aoki2, and Atsushi Senoo1

1Graduate School of Human Health Sciences, Tokyo Metropolitan University, Tokyo, Japan, 2Department of Radiology, Juntendo University School of Medicine, Tokyo, Japan, 3Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

The purpose of this study was to assess whether contrast-enhanced synthetic MRI is suitable for detecting brain metastases by comparing the lesion-to-white matter contrast, contrast-to-noise ratio, and number of brain metastases detected in synthetic and conventional magnetic resonance images. Synthetic T1IR images had better contrast compared with synthetic T1W or conventional T1IR images. Synthetic T1IR images enabled detection of more metastases than did synthetic T1W and conventional T1IR images even though statistical significance was not detected. Contrast-enhanced synthetic T1IR is useful for detecting brain metastases. Further optimization of contrast weighting is needed to maximize the ability to detect brain metastases. The purpose of this study was to assess whether contrast-enhanced synthetic MRI is suitable for detecting brain metastases by comparing the lesion-to-white matter contrast, contrast-to-noise ratio, and number of brain metastases detected in synthetic and conventional magnetic resonance images. Synthetic T1IR images had better contrast compared with synthetic T1W or conventional T1IR images. Synthetic T1IR images enabled detection of more metastases than did synthetic T1W and conventional T1IR images even though statistical significance was not detected. Contrast-enhanced synthetic T1IR is useful for detecting brain metastases. Further optimization of contrast weighting is needed to maximize the ability to detect brain metastases.

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