Abstract #1362

Apparent diffusion coefficient in preoperative grading of gliomas: a comparison between ultra-high and conventional mono-b value diffusion-weighted MR imaging

YuChuan Hu¹, LinFeng Yan¹, ZhiCheng Liu¹, YingZhi Sun¹, DanDan Zheng², TianYong Xu², Wen Wang¹, and GuangBin Cui¹

¹Department of Radiology, Tangdu Hospital, Fourth Military Medical University, Xi’an, China, People's Republic of, ²MR Research China, GE Healthcare China, Beijing, China, People's Republic of

The preoperative grading of gliomas, which is critical for determination of the most appropriate treatment, remains unsatisfactory. As an improved MRI technique, diffusion-weighted imaging (DWI) is considered the most sensitive for early pathological changes and therefore can potentially be useful in evaluating the glioma grades. Recently, apparent diffusion coefficient (ADC) values derived from the high (3000 sec/mm2) b values DWI were reported to improve the diagnostic performance of DWI in differentiating high- from low-grade gliomas5. But a mono-exponential model and relatively lower high-b values were used in this study.We used a tri-component model to calculate ultra-high ADC (ADCuh) in our research, aiming to retrospectively compare the efficacy of ultra-high and conventional mono-b value DWI in the glioma grading.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.