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Abstract #1384

Differentiation of glioblastoma multiforme and single brain metastasis by the distribution pattern of intratumoral susceptibility sign derived from susceptibility-weighted imaging

Hyunkoo Kang1 and Keuntak Roh1

1Department of Radiology, Seoul Veterans Hospital, Seoul, Korea, Republic of

Susceptibility-weighted imaging (SWI) is an emerging magnetic resonance imaging (MRI) technique that exploits the susceptibility differences between the tissues. SWI provides the enhancement of small vessels and microhemorrhages and detection of iron in the brain. These characteristics permit SWI to show anatomical and functional heterogeneity of brain tumors by exquisite sensitivity to the blood products and venous vasculature. The aim of this study is to determine whether the distribution pattern of intratumoral susceptibility sign (ITSS) derived from SWI could differentiate glioblastoma multiforme (GBM) and single brain metastasis. We investigated the distribution patterns of ITSS of the tumors and applied an ITSS grading system based on the degree of the ITSS. Then, we compared the grade of the visibility of ITSS in the central portion of tumors (CITSS) and in the tumor capsular area (PITSS) on SWI in consensus. In clinical use, SWI is also useful for differentiating GBMs from metastases.

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