Abstract #1385

Differentiating contrast-enhanced glioma from peritumoral edema using the intravascular fraction derived from IVIM MRI - a comparative study with DSC MRI

Yen-Shu Kuo^1,2, Han-Min Tseng³, and Wen-Chau Wu⁴

¹Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan, ²Radiology, Cathay General Hospital, Taipei, Taiwan, ³Neurology, National Taiwan University Hospital, Taipei, Taiwan, ⁴Graduate Institute of Oncology, National Taiwan University, Taipei, Taiwan

In this study, we performed intravoxel incoherent motion (IVIM) MRI in 25 patients with histologically proven gliomas, and compared the intravascular fraction f with the cerebral blood volume derived from dynamic susceptibility-contrast (DSC) MRI (CBV_DSC). Results showed that f was able to differentiate contrast-enhanced glioma from peritumoral edema by detecting elevated vascularity. Cross-modal comparison indicated that f correlated better with contrast-leakage-corrected CBV_DSC than uncorrected value.

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