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Abstract #1395

DTI-based connectome analysis of adolescent depression reveals hypoconnectivity of the right caudate

Olga Tymofiyeva1, Colm G Connolly1, Tiffany C Ho1, Matthew D Sacchet2, Eva Henje Blom1,3, Kaja Z LeWinn1, Duan Xu1, and Tony T Yang1

1UCSF, San Francisco, CA, United States, 2Stanford University, Stanford, CA, United States, 3Karolinska Institutet, Stockholm, Sweden

The goal of this study was to perform DTI-based connectome analysis in a cohort of depressed adolescents and matched non-depressed controls. Our findings highlight the role of right caudate connectivity, in particular to frontal gyri, insula, and anterior cingulate, in this population.

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