Meeting Banner
Abstract #1399

Simultaneous Real-time fMRI and EEG Neurofeedback for Emotion Regulation Training in Depressed Patients

Vadim Zotev1, Raquel Phillips1, Masaya Misaki1, Ahmad Mayeli1,2, and Jerzy Bodurka1,3

1Laureate Institute for Brain Research, Tulsa, OK, United States, 2Electrical and Computer Engineering, University of Oklahoma, Tulsa, OK, United States, 3College of Engineering, University of Oklahoma, Tulsa, OK, United States

We have performed an exploratory study of emotion self-regulation training in major depressive disorder (MDD) patients using simultaneous real-time fMRI and EEG neurofeedback (rtfMRI-EEG-nf). MDD patients learned to upregulate two fMRI and two EEG target measures, relevant to MDD, using rtfMRI-EEG-nf during a happy emotion induction task. The target measures included fMRI activities of the left amygdala and left rACC, as well as frontal EEG asymmetries in the alpha and high-beta bands. Our results demonstrate that MDD patients can learn to successfully upregulate all four measures simultaneously. These findings may lead to development of more efficient neurotherapies for MDD.

This abstract and the presentation materials are available to members only; a login is required.

Join Here