Abstract #1425

DCE derived kinetic perfusion indices predict seizure control in single calcified Neurocysticercosis

Alok Kumar Singh¹, Ravindra Kumar Garg¹, Prativa Sahoo², Hardeep S Malhotra¹, Pradeep Kumar Gupta³, Nuzhat Husain⁴, and Rakesh Kumar Gupta³

¹Department of Neurology, KG Medical University, Lucknow, India, ²Healthcare, Philips India ltd, Bangalore, India, ³Radiology and Imaging, Fortis Memorial Research Institute, Gurgaon, India, ⁴Pathology, Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India

The purpose of this study was to investigate the utility of DCE derived kinetic parameters and serum MMP-9 in predicting the control of seizures in patients with calcified NCC while these are on AED therapy. We found that during follow up, K_ep and K^trans values decreased significantly in no recurrence group while increased in recurrence group. The serum MMP-9, a marker of BBB breakdown also supported the DCE derived kinetic metrics. Our results suggest that DCE derived kinetic parameters, might be able to predict the control of seizures in patients with single calcified NCC while these are on AED therapy

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