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Abstract #1425

DCE derived kinetic perfusion indices predict seizure control in single calcified Neurocysticercosis

Alok Kumar Singh1, Ravindra Kumar Garg1, Prativa Sahoo2, Hardeep S Malhotra1, Pradeep Kumar Gupta3, Nuzhat Husain4, and Rakesh Kumar Gupta3

1Department of Neurology, KG Medical University, Lucknow, India, 2Healthcare, Philips India ltd, Bangalore, India, 3Radiology and Imaging, Fortis Memorial Research Institute, Gurgaon, India, 4Pathology, Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India

The purpose of this study was to investigate the utility of DCE derived kinetic parameters and serum MMP-9 in predicting the control of seizures in patients with calcified NCC while these are on AED therapy. We found that during follow up, Kep and Ktrans values decreased significantly in no recurrence group while increased in recurrence group. The serum MMP-9, a marker of BBB breakdown also supported the DCE derived kinetic metrics. Our results suggest that DCE derived kinetic parameters, might be able to predict the control of seizures in patients with single calcified NCC while these are on AED therapy

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