Sudhanya Chatterjee1, Dattesh D Shanbhag1, Uday Patil1, Venkata Veerendranadh Chebrolu1, and Rakesh Mullick1
In acute ischemic stroke (AIS), stroke volume is determined by DWI and
volume at risk is identified by thresholding deconvolved Tmax map (> 6s).
Tmax map is itself influenced by quality of AIF, its location, laterality and
deconvolution algorithm. This can potentially impact estimation of "volume
at risk”. In this work, we describe a CAMNS based source separation
method with DSC concentration data to identify perfusion
patterns without explicit parametrization of PWI data. We
demonstrate that "volume at risk" estimation derived with CWSE may
overcome the variability associated with the current methods based on Tmax
maps only.
